aged twenty-four, American, tained hyaline casts with granular epithelium. months, eight from beginning of last attack. Mind and body failed together and she died in No autopsy. Urine contained waxy and granfour and one-half months, eight and one-half ular casts. months from the beginning. Pulmonary Case 21. tuberculosis developed in the later stages. single, domestic; was "running down" in health for an indefinite time. Melancholia of restless type; rapid decline with development of tuberculosis. Urine contained a small amount of albumin. Died in four months. Case 22. Autopsy: Granular, contracted kidneys; tuberculosis of lungs; mitral stenosis of heart. Case 19. aged past fifty, married, no children, Irish; a niece insane. Had been considered fairly well up to about two months Autopsy: Granular, contracted kidneys; tubefore admission, when she began to worry berculosis of lungs; mitral stenosis of heart; about trifles and developed hallucinations of fatty liver. sight and hearing; attempted suicide by cutting abdomen with a razor because she was "tired of herself." On admission, the urine contained hyaline casts; tendency to obesity, with flabby flesh and sluggish circulation; albumin and hyaline casts. There was a mitheart-sounds feeble. This patient seemed ral systolic murmur of the heart. No autopsy. more hypochondriacal than truly melancholy; - aged sixty, Pennsylvania her attention could generally be diverted and at times she was even cheerful. Her suicidal intentions were not much credited until one aged sixty-six, American, widow. Melancholy for one year before admission, and committed suicide by hanging herself two months later. Case 23. German, widow. Urine contained Whole duration nine and one-half Restless melancholia with years. keenest apprehensions constantly present. In the early stages would look out of the window and scream "The sky is coming down!" "We shall all be burned up" in an agony of fear. Terminated in partial dementia of melancholic Autopsy: Case 34. aged sixty-five, American, widow, one daughter whose mental capacity seemed below the average. Two weeks before admission arose in the night and tried to set fire to the house. Condition that of restless melancholia of rather quiet type. Lived six and one-half years; without remissions; tendency to dementia slight. Autopsy: Kid month after her admission to the hospital, she managed to secrete a table-knife and cut her own throat almost "from ear to ear," half severing the trachea, but no important vessels. This was followed by an amelioration type, with extreme emaciation. of the mental symptoms. The wound kept Kidneys, cortex almost entirely destroyed by in healthy condition and had healed to within fatty change. Heart, atheroma and thickenone and a half inches (small opening into the ing of valves; calculus in gall-bladder. trachea remained) at the time of her death, which was two months from the time of her admission, four from the beginning of her insanity. She was constantly threatened with heart-failure, and her death, occurring very suddenly, was evidently due to that cause. Autopsy Kidneys a little swollen in appearance; capsule not adherent; cortex thin, friable, and of yellowish color, containing some neys, contracted with extensive destruction of cortex. Heart-valves thickened. Lungs tucysts; pelves dilated and injected. Heart berculous. flabby and fatty, valves thickened and atheromatous. Liver large and fatty. Right lung contained, in posterior part of lower lobe, a gangrenous area, two by three inches, circumscribed by inflammatory adhesions of the adjacent pleura. Brain not examined. "DURING my stay in America I used Tongaline wherever indicated with such excellent results, that I desire to learn if the preparation can be obtained in this country. Case 20. aged seventy-two, American, married; two brothers committed suicide. Suicidal melancholia of six months' duration; had a similar attack three years before from which she apparently recovered. Lived two of the JoURNAL. "OTTO FRISONI, M. D., Read the new advertisements in this issue Kansas Medical Journal. PUBLISHED MONTHLY. SUBSCRIPTION PRICE, INCLUDING POSTAGE: Per Annum, in advance.............. 25 Cents. Subscription may begin at any time. The safest mode of remitttance is by bank check or postal money order drawn to the order of the undersigned. When neither is accessible, remittances may be made at the risk of the publishers, by forwarding in REGISTERED LETTER. Address Kansas Medical Journal, Editor-in-Chief: of fright or violence. According to Gray, "the uterus continues to enlarge up to the sixth month of gestation. This enlargement is particularly due to increased development of pre-existing and new-formed muscular tissue. The round ligaments are enlarged, and the $200 broad ligaments become encroached upon by the uterus, making its way between their laminæ. The mucous membrane becomes more vascular, its mucous follicles and glands enlarged; the rugae and folds in the canal of the cervix become obliterated; the blood and lymphatic vessels, as well as the nerves accordto the researches of Dr. Lee, "greatly enlarged." The conditions are present favoring innovation from without and from within. Such as fright and strong mental impressions. Interference with the general system by way of W. A. PHILLIPS, M. D., Salina. drastic cathartics, emetics or antipyretics and T. W. PEERS, M. D., Topeka. depressents, such as podophyllin, turpeth mineral, antipyrin, or large doses of quinineor due to a miasm. 723 Kansas Avenue. J. E. MINNEY, A. M., M. D., Topeka, Kas. Assistants: W. L SCHENCK, M. D., Osage City, Kas. W. D. BIDWELL, M. D., Leavenworth. W. F. SAWHILL, M. D., Concordia. TOPEKA, KANSAS, DECEMBER, 1890. Quinine in Pregnancy. The statement goes the rounds of the journals periodically, "that large doses of quinine in the early months of pregnancy is liable to induce miscarriage." This is doubtless true of certain idiosyncrasies. If given indiscriminately and unreasonably it may be true of all. The same may be said of a large number of therapeutic agents given in toxic doses. Not that there is a selective affinity for the uterus by them, but it is due to the nervous shock. The strength of a chain is determined by its weakest link. In these latter days but few uteri, according to gynaecologists, are normal in structure or function, and the uterus is the weak link of the system. Although designed by nature for the purpose of receiving and developing the embyro, should the uterus be normal, the changed physiological condition present increases the susceptibility of the sympathetic nervous system. The attention of the uterus is absorbed all the while now in adjusting itself to its new relation and making preparation for future greatness. At this time it is off its guard, as it were, and not prepared for surprise by way The conclusion we come to from reasoning and experience is, that quinine when indicated, and given in corresponding doses to the malignancy of the disease, is no more dangerous than the drugs mentioned, in early preg nancy. In some of the malarial affections where quinine is given the former is the cause of the accident and not the latter. What too large a dose would be in malignant malaria would be difficult to state, but enough should be given even in early pregnancy to meet the indications. GERMAIN SEE recommends large doses of bi-carbonate of soda, forty-five to sixty grains, dissolved in warm water to be given at the time of the greatest acidity of the stomach which is generally two hours after meals. A cousin of ours was in the habit of taking from one to four drachms of the bi-carbonate of soda two and three times a day for ten years for acidity of the stomach. His business required him to live one year, 1882, in Cherokee county, Kas., where he used the alkali water of the country for home use, and a perfect cure was effected within six months which continues to the present time. DR. BROADBENT, in an address before the British Medical association, says a mark of a weak medical man, "is the indiscriminate use of stimulants in fevers, a ready resort to narcotics and sedatives, treatment directed to symptoms only and a fondness for new drugs of high sounding name."-Medical Record. Done Likewise. Dr. R. S. Magee of the firm Minney & Magee, seeing the notice of the taking off of Dr. M. H. Cazier in the last number of the JOURNAL and the advice there given to bachelors to go and do likewise," did it. The JOURNAL DR. DAVID WEBSTER, in a paper on "Foreign cannot joke even without some fellow acting Bodies in the Eye," lays stress upon a careful the joke in earnest. The doctor was most search for them. He reports the case of a lady fortunate however in securing a prize worth who visited a reputable physician who had having in the person of Miss Gertie L. Easter, been treating her for more than a week for of Burlingame, Kas. The happy event occuracute inflammation of the eye. Upon her red on Tuesday, November 4, 1890, election visiting him and being told he found a foreign day, and the doctor was one of the republibody at the sclero corneal junction, she declared it had always been there. The doctor had accepted her statement that it had always been there. This shows how unreliable statements of patients may be, and that we should always carefully examine the eye by daylight and focal illumination,especially when only one eye is affected. If we can find no foreign body then examine the condition of the lachrymal sac and duct,since inflammations of these appendages are a frequent cause of monocular inflammation. cans who was ELECTED. Dr. and Mrs. Magee are at home to their friends, No. 713 Monroe street. We know a few more bachelor physicians who would make good women husbands, but seeing how our advice is acted upon we begin to think it is worth something and will wait for a consideration before we repeat it. The congratulations of the JOURNAL are extended to the doctor and wife, and they are referred to Psalm 128, as to what shall be. THE sixteenth annual report of the Cincinnati Sanitarium has been received. It is a lum. The writer hereof has had the fortune DR. NICHOLAS SENN made a rather amusing error while demonstrating his hydrogen gas test in abdominal injuries before the Berlin congress. A dog was brought in and the good advertisement for a private insane asydelusive tube inserted and gas turned on. Then there was a wait of nearly ten minutes to send several patients from his private pracbut no gas appeared. Upon closer examination it was found that the tube was introduced into the vagina instead of anus, when the error was corrected. AMONG the many great improvements which are now being made in the manufacture of physician's instruments and office appliances we are pleased to note something new in the way of an adjustable sofa, manufactured by Clark, Forbes & Co., of Miamisburg, Ohio. This sofa called Nedöfik sofa, certainly comes nearer meeting the requirements of the general practitioner and the specialist who requires an operating chair or table, than any thing we Its neatness, simplicity, and ease of manipulation are features which certainly recommend it. The ready sale and increasing demand, evidence the approval of the physicians. have seen. tice to the Kansas asylum at Topeka, and in every case a recovery has ensued. This speaks well for the institution, but the writer also claims some of the credit, from the fact that he sent the cases at the first unmistakable manifestations of insanity, and did not wait for the cases to become incurable before con signing them to the only place where they could receive the proper treatment. LITTLE THINGS. hospitality, and we hope that the doctor may experience an abundance of the aforesaid Dr. C. H. GUIBOR has removed his office to article. 719 Kansas avenue. COMPLETE anæsthesia should be established DR. J. M. JENNINGS of Wamego, Kansas, before beginning a surgical operation and concalled on us recently. Dr. G. A. WALL occupies rooms in the Stephenson & Peckham building 717 Kansas avenue. DR. H. FAGAINES of Leoti, Kas., has been a Topeka visitor for some weeks; and has con cluded to locate here. INFLUENZA AGAIN.-Influenza or "La Grippe" is making its appearance in many places both in this country and in Europe. BLINDNESS, supposed to be hysterical, is prevailing as an epidemic among the factory girls in Wheeling, West Virginia. THE Medical Era says that there are in the world only 13,000 homopathic physicians, while there are more than 200,000 old-school physicians. DR. J. C. MCCLINTOCK, professor of surgery in the Kansas Medical College, has withdrawn from the general practice of medicine and devotes his whole time to surgery. AT a recent meeting of the Medical Society at Mount Vernon, New York, there was a base ball match between the qui-nines of Mount Vernon and the strych-nines of Younkers.Baltimore Medical and Surgical Record. Dr. J. H. BENEPE of Kingman, Kansas, was a pleasant caller last month. He visited the Kansas Medical College, and expressed himself well pleased. We are always glad to see you, doctor. THE Colorado State Board of Health has ruled that diplomas of schools not having a compulsory three years' course of not less than five months in each year, will not be accepted after July 1, 1893. THE London Lancet is authority for the statement-that the day is probably not far distant, when persecution, ostracism or censure for difference of opinion in belief, will be regarded as not only immoral but absurd. A LETTER from Dr. A. B. Freeman informs us that he has removed from Joplin, Mo., to Atlanta, Ga. The South is proverbial for its tinued to the end. Letting a patient come out from under the influence sufficient to experience pain in taking the last suture is liable to produce dangerous shock. A MEMBER of the JOURNAL association having inculcated Republican principles in his family, was surprised at the breakfast table, when reading of a burglary, to hear his youthful offspring say, "Well, papa, I suppose all burglars are Democrats, are they not?” QUININE IN EARLY PREGNANCY.-Mrs. H., finding herself in an uninteresting condition i.e. pregnant-took fifty-one grains of quinine for the purpose of "bringing on her turns," as she expressed it. Complete cinchonism resulted, but the little one remained unhurt. AMONG our exchanges we see the first number of the Baltimore Medical and Surgical Record. In view of the "extenuating circumstances" as given in the salutatory, by the worthy editor,, we extend a "highland wel come." DR. SCHENCK recommends in the treatment of erysipelas drachm doses of Tr. Fer. Chlor. every 6 hours, and every 6 hours 10 drops of saturated solution of bi-sulph. soda, given 3 hours apart, keeping the local expression moistened with a dilute solution of the bisulph., always taking care that the bi-sulph is bi-sulph. THE Academy of Medicine and Surgery of Topeka closed the most successful year of its existence November 4, 1890. Dr. Munn, the President and Dr. Rodgers, the Secretary, are jusly entitled to the plaudit, "Well done good and faithful servants." Dr. Munn not caring to serve again was succeeded by Dr. Peers as president. Dr. Rodgers succeeds himself. DR. W. H. RIGHTER, professor of genitourinary diseases and dermatology in the Kansas Medical College, is authority for the statement that "prohibition is a prophylaxis against venereal diseases." In other words since the prohibitory liquor law of Kansas went into effect gonorrhoea has become almost extinct and would cease to exist if it was not for the imported cases. The above coming from a strong resubmissionist is good temperance literature. A Letter. The November number of the "KANSAS MEDICAL JOURNAL" appears in its usual garb, HYPNOTISM. The Russian government clean, bright and attractive. Its leading arhas recently forbidden public seances of hypnotism, and the application of it to the treatment of disease is only allowed in the presence of several medical men.-N. Y. Med. Record. cans. ticle, by Dr. Daily, on "Aseptic Surgery," is a fitting reflex of the chaste little journal that prints it. Its mechanical construction indicates clean hands and clean instruments. Ar the Tenth International Congress there Its subject matter clean, good morals and clear were present more than six hundred Ameri- thought. Its reports of numerous societies When the announcement was made it show a wonderful progress of the profession was greeted with a burst of applause, which, in the state for the last ten years, and fully says, A. Jacobi, of New York, "fathered the justify the demand for a "State Society Jourpride of every American present." nal." As an ex-member of that society I IMPAIRED hearing, the result of chronic second the motion, and nominate this JOURcatarrh of the middle ear, is greatly improved NAL for the position, with the prediction that before another decade shall have passed away, by the use of a small-sized London hearing horn, which can be concealed in the closed its growing usefulness and patronage will hand, held at the side of the head, and tucked force it into a conspicuous place among the away in the pocket when no longer needed. AT THE Mississippi Valley Medical Society, Dr. H. N. Mayes of Chicago, spoke of the hypodermic method of administering arsenic as much safer than when given by the mouth. A much larger dose may be given, and continued without causing toxic symptoms, Dr. Hammond having given as much as 50 drops. of Fowler's solution as an initial dose. Dr. Mayer has often given arsenic by the mouth until the eyes were suffused and face puffy, and vomiting incessant; then changed to the hypodermic method and with a larger dose, the gastric symptoms quickly subsiding, and the disease under treatment promptly cured. great metropolitan weeklies of the country. It is said that in Kansas "the unexpected always happens." "Three double births" in one family abundantly establishes the law of heredity by the "double rule of three," while the two factors "65 (?) years of age,” and “ten minutes time," only show how things move when once they get started in Kansas. In answer to your query, "What is the poison of the bee?" It is one of the many secretions of the apis melifica; owes its mischievous potency, (and possibly its medicinal virtues) to "certain pungent salts." It "dries into clear, sharp-pointed, oblong crystals." I have never used it in rheumatism; have had some experience in its action when hypodermically administered by Dr. Bee herself. She is an enthusiastic little practitioner; "sings as she toils;" is a stickler for the code; uses a barbed needle, leaves it in the wound, and suffers the death penalty for mal-practice. (See Encyc. Brit.) MEDICINES that irritate the mucous membrane of the stomach and weaken the digestion, besides forming insoluble compounds with the pepsin and acid of the stomach, as bile arsenic, the salicylates, quinine, &c., should be coated with keratin, as this is insoluble in the fluids of the stomach, and dissolves In closing these notes the writer must rereadily in the intestinal juices. Those phy- cord another "coincidence:" Like your sicians desiring to administer medicines like Osage City contributor, he is "a bee-keeper" the above-mentioned, can have pills keratin on a small scale, and is also coated by sending formulæ to Reed & Carnrick, Park, Davis & Co., and perhaps any of the manufacturing chemists, and thus be able to give the remedies adapted to cases without the usual unpleasant symptoms so common when given in the usual form. OSAGE CITY, KANSAS. J. T. SHEPARD. WE hear not a little about elevating the dignity of the profession nowadays, but it is sel |