PRIZE ESSAY.

ON THE

PATHOLOGY OF JAUNDICE.

THE YELLOW COLOR OF THE SKIN DUE TO THE PRESENCE OF HEMATOIDINE.

BEING THE

PRIZE ESSAY TO WHICH THE AMERICAN MEDICAL ASSOCIATION AWARDED THE GOLD MEDAL FOR MDCCCLXIV.

BY

S. FLEET SPEIR, M. D.,

SURGEON TO THE BROOKLYN CITY DISPENSARY; CURATOR AND MICROSCOPIST TO THE BROOKLYN CITY
HOSPITAL; DEMONSTRATOR OF ANATOMY IN THE LONG ISLAND COLLEGE HOSPITAL;

FELLOW OF THE NEW YORK ACADEMY OF MEDICINE; MEMBER OF THE
NEW YORK PATHOLOGICAL SOCIETY, ETC.

Dermocholepoesis.

DESCRIPTION OF THE PLATES.

THE plates represent the microscopic appearances of the tissues, magnified 250 diameters. On account of the great similarity of these cases, the illustrations may be applied indiscriminately to any of the cases.

PLATE I.

Fig. 1.-BLACK VOMIT.-a, Granules of hæmatoidine; b, Sarcinæ ventriculi; c, Muscular fibre from ingesta; d, Altered starch corpuscles; e, Blood-corpuscles ;

f, vibriones; a few oil-globules are seen.

Fig. 2.-LIVER.-a, Liver-cells; b, Granules of hæmatoidine; c, Blood-crystals.

Fig. 3.-KIDNEY.-a, Granules of hæmatoidine; b, Blood crystals; c, One of the tubuli uriniferi and epithelium.

Fig. 4. SPLEEN.-a, Granules of hæmatoidine; b, Altered blood-corpuscles; c, Fusiform cells.

Fig. 5.-URINE.-a, Granules of hæmatoidine; b, Blood-corpuscles; c, Epithelium from bladder; d, Epithelium from pelvis of kidney; e, Epithelium from ureter; f, Urate of ammonia.

PLATE II.

Fig. 1.-CONJUNCTIVA.-a, Fibrous tissue; b, Granules of hæmatoidine.

Fig. 2. SKIN.-a, Fibrous tissue; b, Granules of hæmatoidine; c, Epithelium; d, Fat

cells.