PART III. NOTES AND FORMULÆ. Hydrogen Peroxide as a Remedy for Whooping Cough. B. W. Richardson. (Pharm. Journ., from Asclepiad, February, 1887.) The author speaks very highly of peroxide of hydrogen as a remedy in whooping cough. In his opinion it acts in a manner very similar to dilute nitric acid, but with more effect, subduing the spasmodic paroxysm, checking the secretion in the throat, and shortening the duration of the malady. His formula for prescribit is-Hydrogen peroxide (10 vols.), 3vj.; glycerin, ziv.; water to Ziij. Dose, half a fluid ounce in a wineglassful of water five or six times a day. Hydrogen Peroxide in Catarrhal Affections. J. N. Mackenzie. (Phil. Med. Times., 1887, 268.) The author directs attention to the use of hydrogen peroxide in 4 per cent. solution for catarrhal affections attended by profuse muco-purulent discharge, used in doses of a fourth to half an ounce three, four, or even six times a day; for topical use he prefers a 6 per cent. solution. By some persons even weaker solutions cannot be used, on account of their irritating effect upon the air passages. marked improvement in the gastric functions was incidentally observed during its administration. Indeed, so striking has been its effects in this regard that it is worthy of more extended trial in obstinate stomachic derangement. A Ethereal Oxygen. B. W. Richardson. (Chemist and Druggist, February 12, 1887.) The author places in a Wolff's bottle, with an inhaling mouthpiece attached to one neck, 2 ounces or more of ozonic ether, the ethereal solution of peroxide of hydrogen. To this he adds, gradually, a solution of permanganate of potash-8 grains to 1 ounce of water-by the other neck of the bottle, and then corks that neck. As the fluids commingle, oxygen gas and ether vapour are given off freely, and can be inhaled from the mouthpiece. The compound of gas and vapour, anesthetic, antispas modic, and respirating, is applicable to a large class of cases of disease, such as pertussis, asthma, and phthisis. Terpine in Neuralgia. M. Ducroux. (Brit. Med. Journ., January 8, 1887, 79.) The author recommends the use of terpine in some forms of neuralgia. He has given it in doses of 60 centigrams in three pills, to be taken between meals. Cannabis Indica in Headache. S. Mackenzie. (Brit. Med. Journ., January 15, 1887.) Indian hemp is recommended by the author as being very useful in headaches of a continuous or chronic character. He has used the extract with success in doses of half a grain night and morning, gradually increased to two grains at night and one and half in the morning. Diuretic Effects of Calomel. Dr. Jendrafsik. (Therapeutic Gazette, 1886, 471.) The author states that he accidentally discovered that calomel produced a powerfully diuretic effect in a case of dropsy, and that he has since then tried it in a number of cases, and always with success. He gives 3 grains three or four times in twenty-four hours. Cocaine in Dysentery. R. L. Hinton. (Therapeutic Gazette, August, 1886, 489.) The author directs attention to the value of cocaine hydrochlorate to relieve pain and tenesmus in dysentery. He administered it in the form of an injection of 2 or 3 drachms of a 4 per cent. solution, with the most successful results. Chloroform as a Styptic. Dr. Ipaak. (Pharm. Journ., from Brit. Journ. Dental Science, Aug. 1886, 704.) The author recommends the use of chloroform as a hæmostatic in dentistry. The solution used consists of 2 parts of chloroform in 100 parts of water. The use of chloroform applied to the crown of the tooth on cotton-wool, to deaden the pain caused by the pressure of the forceps on the sensitive dentine, has therefore the double advantage, since a hæmostatic action will also be obtained. Chloroform as a Tapeworm Remedy. (Chemist and Druggist, Feb. 19, 1887.) Chloroform has been found very efficient against tapeworms. Doses of 30 grains have been given, repeated after twenty or thirty minutes; but troublesome cardiac symptoms. may be avoided by giving smaller doses (a few drops) every five minutes for a few times. Thompson successfully prescribed chloroform, 3j. (by weight), simple syrup to 3j., to be given in three doses, at intervals of two hours, in the morning, fasting, with castor oil to follow. Application of Boric Acid in Throat Diseases. (Pharm. Journ., 3rd series, xvii. 46.) gregor. A. D. Mac The author recommends a gargle containing boric acid and glycerin, with either tannic acid or alum in addition, in pharyngitis and relaxed conditions of the throat. Application of Quinine as Oleate. R. Rother. (Druggists' Circular, July, 1886.) The method of administering quinine by inunction is coming into practice. For this purpose it is usually exhibited in the form of an ointment prepared by mixing some salt of quinine, usually the sulphate, with a fatty medium. Since the oleate presents superior advantages in this manner of application, such an article has of late appeared in the market. As the quality of the commercial article is variable, and frequently not of good quality, the author recommends the following process for its preparation : Quinine, Anhydrous. Acohol, Water 324 parts. of each sufficient. Mix the oleic acid with its volume of alcohol, and gradually add the quinine, finally warming the mixture, if necessary to effect complete combination, and filter if desirable. Expel the alcohol with a gentle heat, and incorporate a little water with the residue. Set it aside in the open air, occasionally stirring it, until the salt has become firm and perfectly dry. Piperine in Ague. C. S. Taylor. (Pharm. Journ., from Brit. Med. Journ., September 4, 1886, 449.) Some cases of refractory intermittent fever, in which, after the failure of quinine, piperine has been administered with advantage, are reported by the author. In one case, immediately on the appearance of an attack, three grains of piperine were given every hour until eighteen grains had been taken, and on the following day, when the intermission was complete, the same dose was given every three hours. The author remarks also that piperine does not produce the unpleasant symptoms in the head which sometimes follow the use of quinine. Cantharides as a Preventive of Hydrophobia. J. M. Maisch. (Amer. Journ. Pharm., March, 1887.) According to the Brit. Med. Journ., a Russian physician, Dr. Karchewski, has treated three persons, who had been bitten by a rabid wolf, with cantharides plaster applied to the wounds, giving at the same time one grain of powdered cantharides daily for one week. After seven months no symptoms of rabies had appeared. This method of treatment was recommended as being always |